کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8674080 | 1578854 | 2016 | 12 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
To Screen or Not to Screen
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کلمات کلیدی
DETtrue-negativeSLBPSBNLSTERSPCOVDSDBPSALTBTIBConsolidated Standards of Reporting Trials - استانداردهای تلفیقی گزارش های تحقیقاتیEuropean Randomized Study of Screening for Prostate Cancer - بررسی تصادفی اروپایی غربالگری سرطان پروستاتOverdiagnosis - تشخیص بیش از حدSelection bias - تعصب انتخابیDetection bias - تعصب تشخیصLead-time bias - تعویض زمان سربازیComputed tomographic - توموگرافی کامپیوتریTrue-positive - درست مثبتSel - سلولFalse-positive - مثبت کاذبNational lung screening trial - محاکمه ملی غربالگری ریهFalse-negative - منفی اشتباهNELSON - نلسونprostate-specific antigen - پادگن مخصوص پروستاتCONSORT - کنسول
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
کاردیولوژی و پزشکی قلب و عروق
چکیده انگلیسی
Screening is the early detection of a latent disorder by a test to allow early intervention with the aim of improving prognosis. Individual and population perspectives on screening are perceived as opposing interests of patients and the population. In this article, we try to reconcile these perspectives. The individual perspective is based on the clinical experience of a better prognosis at early stages and patients with missed opportunities. In the population perspective, screening is based on a population-oriented, evidence-based model and addresses the acceptability and possible negative effects, including for people without the disorder. Known possible obstacles to a positive effect of screening include a short latent stage, lead time, overdiagnosis, lack of acceptability, poor performance of tests, and misclassification of outcome. Randomized trials of screening are challenging and need an adaptation of standards such as the Consolidated Standards of Reporting Trials (CONSORT). Simulating the effects of screening can allow the consideration of complex screening strategies and other options to help avoid biases related to treatment improvement and prevention success. Reconciling both perspectives is possible by considering that hypotheses underlying the former are prerequisites for the latter. From an evidence-based medicine and policy perspective, we suggest that recommending screening or prescribing a test is unethical if all possible obstacles are not documented by providing the best available evidence.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Mayo Clinic Proceedings - Volume 91, Issue 11, November 2016, Pages 1594-1605
Journal: Mayo Clinic Proceedings - Volume 91, Issue 11, November 2016, Pages 1594-1605
نویسندگان
L. Rachid MD, PhD, Gaëlle MD, PhD, Marion MD, MSc, Simone MD, PhD,