کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8674162 | 1578856 | 2016 | 12 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Potentially Curable Cancers of the Esophagus and Stomach
ترجمه فارسی عنوان
سرطان بالقوه قابل درمان میگرن و معده
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کلمات کلیدی
5-FUSCCGACGastric adenocarcinoma - آدنوکارسینوم معدهoverall survival - بقای کلPositron emission tomography - توموگرافی گسیل پوزیترونEsophageal cancer - سرطان مریGastric cancer - سرطان معده5-fluorouracil - فلوروراسیل-۵، فلوئورواوراسیلhazard ratio - نسبت خطرpathologic complete response - پاسخ کامل پاتولوژیکPET - پتSquamous cell carcinoma - کارسینوم سلول سنگفرشیLymph node - گره های لنفاوی
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
کاردیولوژی و پزشکی قلب و عروق
چکیده انگلیسی
Gastric and gastroesophageal adenocarcinomas continue to be a major health burden globally and collectively represent the third leading cause of cancer death. Among patients with metastatic disease, most die of their cancer because of the limited number of modestly effective treatment regimens available today. The progress against these cancers has been slow compared with many other solid tumors despite many attempts. In-depth molecular profiling has also not been completed. Even when these cancers are localized, they impose considerable challenges for the patient, relatives, and treatment team alike. Localized gastric or gastroesophageal cancer is best managed with a multidisciplinary approach. This review focuses on the management of localized cancers by reviewing the current literature and explaining certain principles that help guide therapy for these patients. The future, however, will afford numerous opportunities, including exploitation of initial data from The Cancer Genome Atlas, to identify novel targets and drugs, harness the prowess of the immune system, and customize therapy for each patient.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Mayo Clinic Proceedings - Volume 91, Issue 9, September 2016, Pages 1307-1318
Journal: Mayo Clinic Proceedings - Volume 91, Issue 9, September 2016, Pages 1307-1318
نویسندگان
Elena MD, MSc, Dilsa MD, Kazuto MD, PhD, Jaffer A. MD,