کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
867601 1470992 2011 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Microcantilevers modified by specific peptide for selective detection of trimethylamine
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آنالیزی یا شیمی تجزیه
پیش نمایش صفحه اول مقاله
Microcantilevers modified by specific peptide for selective detection of trimethylamine
چکیده انگلیسی

We report a biosensor based on a microcantilever that is modified by a specific peptide for highly selective detection of trimethylamine (TMA). The assay is based on binding-induced bending of the peptide functionalized microcantilevers. The sensor is selectively responsive to TMA. The amplitude of microcantilever bending at equilibrium is a function of the concentration of TMA with a dynamic range from 8 ppm to 800 ppm. The detection limit is approximately 8 ppm. There is a good intra-sensor and an acceptable inter-sensor reproducibility as evidenced by the standard deviation of 5% and 15%, respectively.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Biosensors and Bioelectronics - Volume 30, Issue 1, 15 December 2011, Pages 140–144
نویسندگان
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