کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
8679857 1579231 2018 26 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Effect of age and gender on the QTc-interval in healthy individuals and patients with long-QT syndrome
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی کاردیولوژی و پزشکی قلب و عروق
پیش نمایش صفحه اول مقاله
Effect of age and gender on the QTc-interval in healthy individuals and patients with long-QT syndrome
چکیده انگلیسی
Age- and gender-related differences in QTc-interval are most likely the result of changes in sex-specific hormones. Although the exact mechanisms and pathophysiology of sex hormones on the QTc-interval are not known, testosterone appears to shorten the QTc-interval. In females, however, there is a more complex interaction between progesterone and estrogen. In patients with an impaired repolarization, such as long-QT syndrome (LQTS), the effect of these sex hormones on the QTc-interval is more pronounced with a differing sensitivity between the LQTS genotypes.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Trends in Cardiovascular Medicine - Volume 28, Issue 1, January 2018, Pages 64-75
نویسندگان
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