Effect of long-term storage in biobanks on cerebrospinal fluid biomarker Aβ1-42, T-tau, and P-tau values

The levels of CSF biomarkers, Aβ1-42, T-tau, and P-tau, did not significantly change during the maximum period of 12 years of storage at −80°C. Batch variation for Aβ1-42 is a factor that should be controlled for when using historical cohorts.