کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8685644 | 1580353 | 2018 | 24 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Is Toxoplasma gondii playing a positive role in multiple sclerosis risk? A systematic review and meta-analysis
ترجمه فارسی عنوان
آیا توکسوپلاسما گوندی نقش مثبتی در خطر ابتلا به مولتیپل اسکلروزیس دارد؟ بررسی منظم و متا آنالیز
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
ایمنی شناسی و میکروب شناسی
ایمونولوژی
چکیده انگلیسی
Toxoplasmosis is a parasitic disease caused by Toxoplasma gondii with a globally widespread distribution. The aim of this systematic review and meta-analysis was to characterize the association between T. gondii infection and multiple sclerosis (MS). The data were systematically collected from the English electronic databases up to April 2017. The research process resulted in the identification of five studies related to the subject of interest entailing 669 MS patients and 770 controls. The pooled prevalence rates of T. gondii infection in the MS patients and controls were estimated as 32.4% (95% CI: 27.4-38.6) and 39.1% (95% CI: 29.1-50.5), respectively. By random effect model, the combined odds ratio was 0.72 (95% CI: 0.49-1.06) with Pâ¯=â¯.0961. Although this meta-analysis study showed a lower seroprevalence of T. gondii in the MS patients as compared with that in the control group, no significant association was found between toxoplasmosis and MS disease. Further investigations are recommended to determine the detailed association between MS patients and T. gondii infection.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Neuroimmunology - Volume 322, 15 September 2018, Pages 57-62
Journal: Journal of Neuroimmunology - Volume 322, 15 September 2018, Pages 57-62
نویسندگان
Reza Saberi, Mehdi Sharif, Shahabeddin Sarvi, Sargis A. Aghayan, Seyed Abdollah Hosseini, Davood Anvari, Tooran Nayeri Chegeni, Zahra Hosseininejad, Ahmad Daryani,