کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
868667 | 909811 | 2009 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Ultrasensitive electrochemical sensing of the anticancer drug tirapazamine using an ordered mesoporous carbon modified pyrolytic graphite electrode
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آنالیزی یا شیمی تجزیه
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Ultrasensitive electrochemical sensing of the anticancer drug tirapazamine using an ordered mesoporous carbon modified pyrolytic graphite electrode Ultrasensitive electrochemical sensing of the anticancer drug tirapazamine using an ordered mesoporous carbon modified pyrolytic graphite electrode](/preview/png/868667.png)
چکیده انگلیسی
A new ordered mesoporous carbon (OMC) modified pyrolytic graphite electrode (PGE) was prepared to investigate electrochemical behavior of the anticancer drug tirapazamine (TPZ). Compared to the bare PGE, the modified electrode showed an excellent electrochemical response to TPZ. The anodic peak current (Ipa) of TPZ at the OMC/PGE is 180-fold higher than that of the bare PGE. The Ipa is proportional with TPZ concentration in the range of 5.0 × 10−11 to 1.5 × 10−5 mol L−1. The linear regression equations are Ipa (μA) = 0.0000044 + 16.928CTPZ (μmol L−1), with a detection limit (S/N = 3) of 2.0 × 10−11 mol L−1. This proposed method can be potentially used for ultrasensitive electrochemical sensing of TPZ in physiological condition.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Biosensors and Bioelectronics - Volume 24, Issue 11, 15 July 2009, Pages 3391–3394
Journal: Biosensors and Bioelectronics - Volume 24, Issue 11, 15 July 2009, Pages 3391–3394
نویسندگان
Guangzhi Hu, Yong Guo, Shijun Shao,