کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
870473 909869 2006 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Olfactory cell-based biosensor: A first step towards a neurochip of bioelectronic nose
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آنالیزی یا شیمی تجزیه
پیش نمایش صفحه اول مقاله
Olfactory cell-based biosensor: A first step towards a neurochip of bioelectronic nose
چکیده انگلیسی

Human olfactory system can distinguish thousands of odors. In order to realize the biomimetic design of electronic nose on the principle of mammalian olfactory system, this article reports an olfactory cell-based biosensor as a real bionic technique for odorants detection. Effective cultures of olfactory receptor neurons and olfactory bulb cells have been achieved on the semiconductor chip. Using light-addressable potentiometric sensor (LAPS) as sensing chip to monitor extracellular potential of the neurons, the response under stimulations of the odorants or neurotransmitters, such as acetic acid and glutamic acid, was tested. The results demonstrate that this kind of hybrid system of LAPS and olfactory neurons, which is sensitive to odorous changes, has great potential and is promising to be used as a novel neurochip of bioelectronic nose for detecting odors.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Biosensors and Bioelectronics - Volume 22, Issue 2, 15 August 2006, Pages 318–322
نویسندگان
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