کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
870639 1471025 2015 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Operator training simulation for integrating cultivation and homogenisation in protein production
ترجمه فارسی عنوان
شبیه سازی آموزش اپراتور برای ادغام کشت و همگن سازی در تولید پروتئین
کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه مهندسی انرژی انرژی های تجدید پذیر، توسعه پایدار و محیط زیست
چکیده انگلیسی

Operating training simulators (OTS) are virtual simulation tools used for training of process operators in industry in performing procedures and running processes. Based on structured mathematical models of the unit operations of a bioprocess an OTS can train a process operator by visualising changing conditions during the process, allow testing operator actions, testing controller settings, experience unexpected technical problems and getting practice in using prescribed standard procedures for a plant.This work shows the design of an OTS where two sequential steps of a recombinant protein production process, a fed-batch cultivation and a high-pressure homogenisation, are integrated. The OTS was evaluated on a user test group and showed that the OTS promoted and developed their understanding of the process, their capability to identify parameters influencing process efficiency and the skills of operating it.

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ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Biotechnology Reports - Volume 6, June 2015, Pages 91–99
نویسندگان
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