کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
875925 910815 2014 10 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Simulation of longitudinal stent deformation in a patient-specific coronary artery
ترجمه فارسی عنوان
شبیه سازی تغییر شکل استنت طولی در یک شرط عروق کرونر خاص بیمار
کلمات کلیدی
تغییر شکل استنت طولی، استنت ها، اختلال استنت، تجزیه و تحلیل عنصر محدود، مدل خاص بیمار
موضوعات مرتبط
مهندسی و علوم پایه سایر رشته های مهندسی مهندسی پزشکی
چکیده انگلیسی

In percutaneous coronary intervention (PCI), stent malapposition is a common complication often leading to stent thrombosis (ST). More recently, it has also been associated with longitudinal stent deformation (LSD) normally occurring through contact of a post balloon catheter tip and the protruding malapposed stent struts.The aim of this study was to assess the longitudinal integrity of first and second generation drug eluting stents in a patient specific coronary artery segment and to compare the range of variation of applied loads with those reported elsewhere. We successfully validated computational models of three drug-eluting stent designs when assessed for longitudinal deformation. We then reconstructed a patient specific stenosed right coronary artery segment by fusing angiographic and intravascular ultrasound (IVUS) images from a real case. Within this model the mechanical behaviour of the same stents along with a modified device was compared. Specifically, after the deployment of each device, a compressive point load of 0.3 N was applied on the most malapposed strut proximally to the models. Results indicate that predicted stent longitudinal strength (i) is significantly different between the stent platforms in a manner consistent with physical testing in a laboratory environment, (ii) shows a smaller range of variation for simulations of in vivo performance relative to models of in vitro experiments, and (iii) the modified stent design demonstrated considerably higher longitudinal integrity. Interestingly, stent longitudinal stability may differ drastically after a localised in vivo force compared to a distributed in vitro force.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Medical Engineering & Physics - Volume 36, Issue 4, April 2014, Pages 467–476
نویسندگان
, , ,