کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
876692 910859 2007 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Photoacoustic monitoring of the absorption of isotonic saline solution by human mucus
موضوعات مرتبط
مهندسی و علوم پایه سایر رشته های مهندسی مهندسی پزشکی
پیش نمایش صفحه اول مقاله
Photoacoustic monitoring of the absorption of isotonic saline solution by human mucus
چکیده انگلیسی

Viscosity and elasticity are the fundamental rheologic properties of respiratory mucus, and are important determinants of transportability of mucus in the mucociliary system. One technique that permits to monitor indirectly the rheologic properties of any sample is the photoacoustic technique. Using that technique, the absorption of isotonic saline solution by human mucus was monitored. The mucus was obtained from 11 volunteers, divided into two groups: five volunteers presenting pneumology symptoms (group I) and six healthy volunteers (group II). The photoacoustic signal of the mucus absorbing the saline solution was monitored as function of time, with measurements being performed each 10 min, up to 120 min. The resulting curves were fitted to sigmoidal curves to simulate the evolution on time of the photoacoustic signal. A characteristic time for the half saturation of the absorption process was obtained. For group I the time obtained was 23.3 ± 5.3 min and for group II the time obtained was 55.0 ± 7.7 min, both means being significantly different (Student t-test, p < 0.05). This result supports the empirical practice of treating individuals presenting symptoms of airway obstruction with about 30 min of inhalations of isotonic saline solution vapor for the clearance of the airways.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Medical Engineering & Physics - Volume 29, Issue 9, November 2007, Pages 980–983
نویسندگان
, , , , ,