Gold nanocages as contrast agents for two-photon luminescence endomicroscopy imaging

We explored the possibility of using gold (Au) nanocages as a new class of exogenous contrast agents for endomicroscopic nonlinear imaging. The two-photon luminescence cross-section of nanocages was characterized. Two-photon luminescence endomicroscopy imaging of a phantom, cancer cells and biological tissues was performed, demonstrating that Au nanocages can potentially serve as an effective molecular contrast agent for nonlinear endomicroscopy imaging.From the Clinical EditorIn this study, the utility of Au nanocages is described in a variety of settings as effective molecular contrast agent for nonlinear endomicroscopy imaging.

Gold nanocages serve as a contrast agent for two-photon luminescence (TPL) endomicroscopy imaging.Figure optionsDownload high-quality image (199 K)Download as PowerPoint slide