کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
878308 | 911072 | 2009 | 12 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Interaction of colloidal gold nanoparticles with human blood: effects on particle size and analysis of plasma protein binding profiles
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
سایر رشته های مهندسی
مهندسی پزشکی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Interaction of colloidal gold nanoparticles with human blood: effects on particle size and analysis of plasma protein binding profiles Interaction of colloidal gold nanoparticles with human blood: effects on particle size and analysis of plasma protein binding profiles](/preview/png/878308.png)
چکیده انگلیسی
Nanoparticle size and plasma binding profile contribute to a particle's longevity in the bloodstream, which can have important consequences for therapeutic efficacy. In this study an approximate doubling in nanoparticle hydrodynamic size was observed upon in vitro incubation of 30- and 50-nm colloidal gold in human plasma. Plasma proteins that bind the surface of citrate-stabilized gold colloids have been identified. Effects of protein binding on the nanoparticle hydrodynamic size, elements of coagulation, and the complement system have been investigated. The difference in size measurements obtained from dynamic light scattering, electron microscopy, and scanning probe microscopy are also discussed.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Nanomedicine: Nanotechnology, Biology and Medicine - Volume 5, Issue 2, June 2009, Pages 106–117
Journal: Nanomedicine: Nanotechnology, Biology and Medicine - Volume 5, Issue 2, June 2009, Pages 106–117
نویسندگان
Marina A. Dobrovolskaia, Anil K. Patri, Jiwen Zheng, Jeffrey D. Clogston, Nader Ayub, Parag Aggarwal, Barry W. Neun, Jennifer B. Hall, Scott E. McNeil,