Myoepithelioma: Benign or malignant - A diagnostic dilemma

Malignant myoepithelioma of salivary gland which is also known as myoepithelial carcinoma is a rare disease. It has a relatively poor clarification of its biologic behavior, clinicopathologic features and immunohistochemical profile. Presentation may be the same as other benign salivary gland tumors. A high index of suspicion is required to diagnose this rare but malignant condition early and this is especially imperative when there is a recurrent tumor with histopathological examination report of benign findings. We report a case of malignant myoepithelioma of right submandibular gland that underwent surgical excision with neck dissection and chemoradiotherapy without signs of recurrence after treatment.