First-line treatment using high-flow nasal cannula for children with severe bronchiolitis: Applicability and risk factors for failure

In our PICU, HFNC therapy for children with bronchiolitis can potentially decrease the use of nCPAP. In this study, the factor of failure was higher pCO2. Studies to evaluate PCO2 level to discriminate HFNC versus CPAP indication could be useful.