Children with nocturnal enuresis and attention deficit hyperactivity disorder: A separate entity?

In children with primary NE, the presence of ADHD was associated with more severe NE, voiding symptoms and constipation. The severity of voiding symptoms and/or NE was unrelated to the use of stimulant medication. The response to behavioral modification was comparable in both groups. However, patients with ADHD were significantly more responsive to medication for NE compared with behavioral modification, indicating a possible benefit for earlier pharmacological treatment for enuresis in this population subgroup.Table. Demographics and clinical characteristics among children with primary NE and ADHD (study group) and children with NE without ADHD (control group).Study group (N = 95)Control group (N = 95)pGender, male/female67/2867/28-Age, yearsa8.87 ± 2.42 (5-16)8.92 ± 2.49 (5-16)0.91Race0.28 African AmericanN = 44 (46.4%)N = 50 (52.6%) CaucasianN = 33 (34.7%)N = 23 (24.2%) OtherN = 18 (18.9%)N = 22 (23.2%)Total number of clinic visitsa2.19 ± 1.40 (1-8)2.08 ± 1.26 (1-7)0.59DVSS scorea11.53 ± 4.53 (0-21)9.84 ± 3.82 (1-20)0.008Number of wet nights per weeka6.26 ± 1.54 (1-7)5.74 ± 2.05 (1-7)0.047Bristol scorea2.92 ± 0.95 (1-6)3.23 ± 0.87 (2-6)0.024Bold value represents statistically significant p < 0.05.aMean ± standard deviation (range).