Community-onset carbapenem-resistant Klebsiella pneumoniae urinary tract infections in infancy following NICU hospitalisation

These cases illustrate that UTI caused by multidrug-resistant pathogens does not necessarily imply an underlying urinary track anomaly. Hospital acquisition of CRKP may well provoke community-onset multidrug-resistant UTI in infants months later, and this highlights the value of detailed history in patients with unusual pathogens. Cautious use of broad-spectrum antibiotics in NICUs and infection control measures would minimise the spread of multidrug-resistant pathogens in infants in the community.161Figure Timeline of NICU hospitalisation and subsequent CRKP UTI of study participants.