کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
8827627 1610681 2017 31 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Osteoporosis following heart transplantation and immunosuppressive therapy
ترجمه فارسی عنوان
پوکی استخوان پس از پیوند قلب و درمان سرکوب ایمنی
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی عمل پیوند
چکیده انگلیسی
Heart transplantation (HT) remains the ultimate final therapy for patients with end-stage heart failure, who despite optimal medical and surgical treatments exhibit severe symptoms. To prevent rejection of the transplanted organ, HT patients require life-long immunosuppressive therapy. The goal of the immunosuppression is to minimise the risk of immune-mediated graft rejection, while avoiding clinical side-effects. Current immunosuppressive agents have yielded good survival outcome, however, complications of the immunosuppressive therapy, such as impaired bone strength and increased fracture risk, are common among HT patients rendering increased morbidity and mortality rates. The main aim of the present review was to summarise current knowledge on bone strength impairment after HT and concomitant immunosuppressive therapy.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Transplantation Reviews - Volume 31, Issue 4, October 2017, Pages 232-239
نویسندگان
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