کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8838986 | 1613220 | 2018 | 47 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Cortical morphometric changes after spinal cord injury
ترجمه فارسی عنوان
تغییرات مرفومتری کورتیکال پس از آسیب نخاعی
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کلمات کلیدی
آسیب نخاعی، مورفومتری مبتنی بر وکسل، حجم ماده خاکستری، قشر مکرر، قشر حسی، درد عصبی،
موضوعات مرتبط
علوم زیستی و بیوفناوری
علم عصب شناسی
علوم اعصاب سلولی و مولکولی
چکیده انگلیسی
We performed a systematic review of the neuroimaging studies showing morphometric cortical changes and subsequent functional reorganization in humans with SCI. Literature search was conducted using PubMed and Embase. We identified 12 articles matching the inclusion criteria and 195 patients were included in these studies. The wide range of disease duration, rehabilitation training, drug intervention, and different research methodology, especially the identification of region of interest and the statistical approach to correct for multiple comparisons, may have contributed to some inconsistencies between the reviewed studies. Nevertheless, neuroimaging biomarkers can assess the extent of neural damage, elucidate the mechanisms of neural repair, and predict clinical outcome. A better understanding of the structural and functional changes that occur at cortical level following SCI may be useful in tracking potential treatment induced changes and identifying potential therapeutic targets, thus developing evidence-based rehabilitation therapies.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Brain Research Bulletin - Volume 137, March 2018, Pages 107-119
Journal: Brain Research Bulletin - Volume 137, March 2018, Pages 107-119
نویسندگان
Raffaele Nardone, Yvonne Höller, Luca Sebastianelli, Viviana Versace, Leopold Saltuari, Francesco Brigo, Piergiorgio Lochner, Eugen Trinka,