کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8840607 | 1614691 | 2018 | 15 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
The Limbic and Sensorimotor Pathways of the Human Amygdala: A Structural Connectivity Study
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کلمات کلیدی
OFCCSDROIHCPNOSDWIConnectomeDTICOV - THEConstrained spherical deconvolution - اختلاط کروی محدود شده استautism spectrum disorders - اختلالات طیف اوتیسمTractography - تراکتوگرافی diffusion-weighted imaging - تصویربرداری با وضوح تصویربرداریdiffusion tensor imaging - تصویربرداری تانسور انتشارCerebral Spinal Fluid - سیالات مغزی نخاعیLateralization index - شاخص توزیعCoefficient of Variation - ضریب تغییرorbitofrontal cortex - قشر اوربیتوفرنتالCSF - مایع مغزی نخاعیRegions Of Interest - مناطق مورد علاقهASD - نقص سپتوم یا دیوارهی دهلیزیEmotion - هیجانHuman Connectome Project - پروژه اتصال انسانی
موضوعات مرتبط
علوم زیستی و بیوفناوری
علم عصب شناسی
علوم اعصاب (عمومی)
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: The Limbic and Sensorimotor Pathways of the Human Amygdala: A Structural Connectivity Study The Limbic and Sensorimotor Pathways of the Human Amygdala: A Structural Connectivity Study](/preview/png/8840607.png)
چکیده انگلیسی
The amygdala plays a key role in gathering social cues to context-appropriate responses that require refined motor behavior, involving either direct or indirect connections with sensorimotor-related areas. Although, several studies investigated the structural and functional limbic connectivity of the amygdala both in animals and in humans, less is known about the limbic modulation on sensorimotor-related areas. However, recent evidences suggest the amygdala as a possible cornerstone in the limbic-motor interface. Herein, we used high-resolution diffusion data of the Massachusetts General Hospital-University of Southern California (MGH-USC) Adult Diffusion Dataset, constrained spherical deconvolution-based signal modeling and probabilistic tractography aimed at identifying and reconstructing the connectivity patterns linking the amygdala to the limbic- and sensorimotor-related areas. As regards the limbic network, our results showed that the amygdala has high probability to be connected with the fusiform gyrus and the lateral orbitofrontal cortex. On the other hand, our connectomic analysis revealed a close interplay between the amygdala and the inferior parietal lobule, followed by the postcentral gyrus, the precentral gyrus and the paracentral lobule. The findings of the present study are in line with previous literature and reinforce the idea of the existence of a limbic-motor interface, which is likely to be involved in the emotional modulation of complex functions such as spatial perception and movement computation. Considering that these pathways may play an important role, not on in physiological conditions, but also in pathological context, further studies should be fostered in order to confirm the existence of a limbic-motor interface and its precise functional meaning.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Neuroscience - Volume 385, 10 August 2018, Pages 166-180
Journal: Neuroscience - Volume 385, 10 August 2018, Pages 166-180
نویسندگان
Giuseppina Rizzo, Demetrio Milardi, Salvatore Bertino, Gianpaolo Antonio Basile, Debora Di Mauro, Alessandro Calamuneri, Gaetana Chillemi, Giuseppe Silvestri, Giuseppe Anastasi, Alessia Bramanti, Alberto Cacciola,