کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8879806 | 1624789 | 2018 | 8 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Sea rose (Armeria pungens (Link) Hoffmanns. & Link) as a potential source of innovative industrial products for anti-ageing applications
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
علوم کشاورزی و بیولوژیک
علوم زراعت و اصلاح نباتات
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
This work explored for the first time the halophyte Armeria pungens (Link) Hoffmanns. & Link (sea rose) as a potential source of industrial natural products with anti-ageing potential. In this sense, ethyl acetate, acetone, ethanol and water extracts were prepared from flowers, peduncles and leaves of sea rose and evaluated for in vitro antioxidant capacity by four complementary methods and enzyme inhibitory effects towards enzymes related with the onset of different diseases, namely acetyl- (AChE) and butyrylcholinesterase (BuChE), α-glucosidase, tyrosinase, lipase and elastase. The polyphenolic composition of the extracts was appraised by high-pressure liquid chromatography coupled with diode array detection analysis (HPLC-DAD). Nineteen phenolic compounds were identified in the extracts, including flavonoids, hydroxybenzoic and hydroxycinnamic acids, and catechin was the main compound detected. The ethanol extract of sea rose leaves was the most effective as DPPH (IC50â¯=â¯83.7â¯Î¼g/mL) and ABTS (IC50â¯=â¯146â¯Î¼g/mL) scavenger, and also as a copper chelator (IC50â¯=â¯81.8â¯Î¼g/mL). The acetone peduncles' extract had the highest iron chelating activity (IC50â¯=â¯142â¯Î¼g/mL). Water and ethanol leaf extracts showed the uppermost AChE inhibition (water: IC50â¯=â¯87.6â¯Î¼g/mL; ethanol: IC50â¯=â¯90.3â¯Î¼g/mL). In turn, the ethanol flower extract had the lowest IC50 values towards α-glucosidase (26.7â¯Î¼g/mL) and tyrosinase (268â¯Î¼g/mL). The leaf ethanol extract had the highest capacity to inhibit elastase (IC50â¯=â¯531â¯Î¼g/mL), while none of the extracts had significant inhibitory activity on BuChE and lipase. In conclusion, ethanol extracts from leaves and flowers of sea rose showed to be the most promising source of natural products for industrial applications, with anti-ageing properties, namely neuroprotective, anti-diabetic, anti-wrinkles and anti-melanogenic activities.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Industrial Crops and Products - Volume 121, 1 October 2018, Pages 250-257
Journal: Industrial Crops and Products - Volume 121, 1 October 2018, Pages 250-257
نویسندگان
Maria J. Rodrigues, Catarina A. Pereira, Marta Oliveira, Nuno R. Neng, José M.F. Nogueira, Gokhan Zengin, M. Fawzi Mahomoodally, LuÃsa Custódio,