Initial development and pilot testing of observer-reported outcomes (ObsROs) for children with cystic fibrosis ages 0-11Â years

An ObsRO for children with CF ages 0-6 appears promising, while self-report may be more appropriate for children > 6 years of age. Next steps for the 0-6 year old instrument will be utilizing it as an exploratory endpoint in clinical trials to enable item reduction, scale development, and further reliability and validity testing. Ultimately, this ObsRO could be a promising endpoint for early intervention trials in young children with CF.