کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8980809 | 1553782 | 2005 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Birth Abnormalities in Pregnant Sows Infected Intranasally with Porcine Circovirus 2
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
علوم کشاورزی و بیولوژیک
علوم دامی و جانورشناسی
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چکیده انگلیسی
Six pregnant sows were inoculated intranasally at 3 weeks before the expected farrowing date with porcine circovirus 2 (PCV2). The PCV2-inoculated sows showed abortion and premature farrowing, whereas two uninfected negative control sows remained clinically healthy and farrowed normally. PCV2 antigen and DNA were detected by immunohistochemistry and in-situ hybridization, respectively, in lymph node, spleen, thymus, lung, tonsil and liver from both stillborn and liveborn piglets. Simultaneous detection of viral protein and DNA provided molecular evidence of PCV2 infection and replication. The experiment suggested that PCV2 is capable of crossing the placenta, replicating primarily in lymphoid tissues, and inducing reproductive failure.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Comparative Pathology - Volume 132, Issues 2â3, FebruaryâApril 2005, Pages 139-144
Journal: Journal of Comparative Pathology - Volume 132, Issues 2â3, FebruaryâApril 2005, Pages 139-144
نویسندگان
J.-S. Park, J. Kim, Y. Ha, K. Jung, C. Choi, J.-K. Lim, S.-H. Kim, C. Chae,