کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
8994174 1114264 2005 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Cation complexing 2-O-alkylated, 3,6-anhydro-α-cyclodextrins: the side-chain length governs physicochemical properties and practical applications
موضوعات مرتبط
علوم پزشکی و سلامت داروسازی، سم شناسی و علوم دارویی اکتشاف دارویی
پیش نمایش صفحه اول مقاله
Cation complexing 2-O-alkylated, 3,6-anhydro-α-cyclodextrins: the side-chain length governs physicochemical properties and practical applications
چکیده انگلیسی
A series of chain-grafted per-3,6-anhydro-a-cyclodextrins (ACD) were synthesized and their cation complexing properties studied by 1H-NMR spectroscopy. Superficial tension measurements, 1H-NMR spectroscopy and phase diagrams showed that the properties of ACD were closely related to LogP, which also controlled their interactions with membranes. As a result, practical applications could be proposed and further perspectives suggested. Hence direct decontamination in liquids may be possible for most amphiphilic derivatives, since these amphiphilic molecules form gels or soaps. The most hydrophobic derivative O36 realizes an insoluble complex that can be used for depollution or cation dosages in liquids.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Drug Delivery Science and Technology - Volume 15, Issue 6, 2005, Pages 419-426
نویسندگان
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