کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
9009840 | 1124087 | 2005 | 5 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Free radical scavenging and hepatoprotective activity of jigrine against galactosamine induced hepatopathy in rats
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کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت
داروسازی، سم شناسی و علوم دارویی
داروشناسی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Free radical scavenging and hepatoprotective activity of jigrine against galactosamine induced hepatopathy in rats Free radical scavenging and hepatoprotective activity of jigrine against galactosamine induced hepatopathy in rats](/preview/png/9009840.png)
چکیده انگلیسی
Jigrine a polypharmaceutical herbal hepatoprotective formulation containing aqueous extracts of 14 medicinal plants is used in Indian system of medicine (Unani). Jigrine was evaluated for its hepatoprotective activity against galactosamine induced hepatopathy in rats. Galactosamine induced hepatotoxicity resembles human viral hepatitis. Biochemical parameters like AST, ALT and urea in serum, TBARS and glutathione in liver and whole blood glutathione were estimated to assess liver function. DPPH-free radical scavenging activity of jigrine was also evaluated. Biochemical data exhibited significant hepatoprotective activity of jigrine against galactosamine. Silymarin used as reference standard also exhibited significant hepatoprotective activity against galactosamine. The biochemical observations were supplemented with histopathological examination of rat liver sections.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Ethnopharmacology - Volume 97, Issue 3, 21 March 2005, Pages 521-525
Journal: Journal of Ethnopharmacology - Volume 97, Issue 3, 21 March 2005, Pages 521-525
نویسندگان
Abul K. Najmi, K.K. Pillai, S.N. Pal, M. Aqil,