کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
9009920 | 1124090 | 2005 | 5 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Analgesic activity of di-caffeoylquinic acids from roots of Lychnophora ericoides (Arnica da serra)
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موضوعات مرتبط
علوم پزشکی و سلامت
داروسازی، سم شناسی و علوم دارویی
داروشناسی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Analgesic activity of di-caffeoylquinic acids from roots of Lychnophora ericoides (Arnica da serra) Analgesic activity of di-caffeoylquinic acids from roots of Lychnophora ericoides (Arnica da serra)](/preview/png/9009920.png)
چکیده انگلیسی
The Brazilian medicinal plant Lychnophora ericoides Mart. (Asteraceae) has been used in traditional medicine to treat wounds, pain and inflammation. As part of our continuing investigation of this commercial phytomedicine, we focused on the polar fractions of the plant, since it is employed as alcoholic and hydroalcoholic preparations. The analgesic bioguided fractionation of the root polar extract yielded 3,5-di-O-[E]-caffeoylquinic acid, 4,5-di-O-[E]-caffeoylquinic acid and 3,4,5-tri-O-[E]-caffeoylquinic acid. The n-butanol fraction and the di-caffeoylquinic acids showed significant analgesic activity in the acetic acid-induced mouse writhing test at low but not at high doses. These findings support, at least in part, the validity of the use of Lychnophora ericoides roots in traditional medicine.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Ethnopharmacology - Volume 96, Issue 3, 15 January 2005, Pages 545-549
Journal: Journal of Ethnopharmacology - Volume 96, Issue 3, 15 January 2005, Pages 545-549
نویسندگان
Michel David dos Santos, Leonardo Gobbo-Neto, Laura Albarella, Glória EmÃlia Petto de Souza, Norberto Peporine Lopes,