In vitro immunomodulatory effect of Pouteria cambodiana (Pierre ex Dubard) Baehni extract

The extract showed low free radical scavenging activity in the 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical assay with an IC50 of 0.24 mg/ml, being less active than ascorbic acid, butylated hydroxytoluene (BHT) and α-tocopherol which showed IC50 of 0.08, 0.10 and 0.11 mg/ml, respectively. The extract at doses up to 0.073 mg/ml had no effect on lipid peroxidation. The potent immunological but no antioxidant activity of the extract presented in this study can explain, at least in part, the Thai folklore application of this plant in the treatment of fever and skin eruption.