کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
9093429 | 1149510 | 2005 | 9 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Enhancing Oxaliplatin-Based Regimens in Colorectal Cancer by Inhibiting the Epidermal Growth Factor Receptor Pathway
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کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
بیهوشی و پزشکی درد
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Enhancing Oxaliplatin-Based Regimens in Colorectal Cancer by Inhibiting the Epidermal Growth Factor Receptor Pathway Enhancing Oxaliplatin-Based Regimens in Colorectal Cancer by Inhibiting the Epidermal Growth Factor Receptor Pathway](/preview/png/9093429.png)
چکیده انگلیسی
In the past several years, significant advances in the treatment of colorectal cancer (CRC) have been made. With the introduction of irinotecan and oxaliplatin combined with infusional 5-fluororuracil, survival times for patients with metastatic CRC have nearly doubled. With the incorporation of biologic agents that target the vascular endothelial growth factor and epidermal growth factor (EGF) pathways, additional improvements in response, progression-free survival, and overall survival have been seen in patients with advanced, metastatic disease. This article reviews the impact of EGF receptor inhibitors on improving survival in CRC when combined with oxaliplatin-containing regimens.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Clinical Colorectal Cancer - Volume 5, Supplement 2, November 2005, Pages S89-S97
Journal: Clinical Colorectal Cancer - Volume 5, Supplement 2, November 2005, Pages S89-S97
نویسندگان
George P. Kim, Axel Grothey,