Apport de la biologie dans le diagnostic de l'allergie médicamenteuse

Discussion. - These results demonstrate that the Elispot IFN-γ in vitro assay provides a method to estimate the number of amoxicillin-specific T cells in peripheral blood. This test appears to differentiate patients who are allergic to drugs from those who are not. The test is interesting because it is simple to carry out, a large number of drugs can be tested at the same time, and the results are obtained rapidly. If these results can be confirmed with other drug molecules, then the ELISPOT IFN-γ in vitro assay could be included in the battery of in vitro tests for delayed hypersensitivity reactions to drugs.