کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
9104595 1153389 2005 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Biological properties and mechanism of action of ibandronate: Application to the treatment of osteoporosis
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی زیست شناسی تکاملی
پیش نمایش صفحه اول مقاله
Biological properties and mechanism of action of ibandronate: Application to the treatment of osteoporosis
چکیده انگلیسی
This review provides details of the general structural features of all bisphosphonates and how these are understood to contribute to their functions in osteoporosis treatment. From this, the unique structure of ibandronate is described, along with how this translates into the high antiresorptive potency, favorable bone-binding, persistence in bone, and good tolerability that permits less frequent dosing. Finally, the clinical evidence for ibandronate is briefly presented, demonstrating the viability of less frequent dosing, with its potential benefits for patient convenience and adherence to therapy.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bone - Volume 37, Issue 4, October 2005, Pages 433-440
نویسندگان
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