کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
9110284 1155009 2005 17 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Adipogenesis: cellular and molecular aspects
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی علوم غدد
پیش نمایش صفحه اول مقاله
Adipogenesis: cellular and molecular aspects
چکیده انگلیسی
Obesity and lipoatrophy are major risks for insulin resistance, non-insulin-dependent diabetes and cardiovascular disease. In the past three decades, significant advances have been made in delineating the key transcription factors of adipogenesis, as well as extracellular effectors and intracellular signalling pathways that regulate fat cell formation. This review focuses on in vitro models of adipocyte differentiation, and on the balance between pro- and anti-adipogenic factors that drive the adipocyte differentiation process. Full understanding of the mechanisms of adipose tissue differentiation represents a major issue to develop a comprehensive strategy to prevent and treat obesity.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Best Practice & Research Clinical Endocrinology & Metabolism - Volume 19, Issue 4, December 2005, Pages 483-499
نویسندگان
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