کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
9121299 1159183 2005 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Osmotic stress and phosphate limitation alter production of cell-to-cell signal molecules and rhamnolipid biosurfactant by Pseudomonas aeruginosa
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی ژنتیک
پیش نمایش صفحه اول مقاله
Osmotic stress and phosphate limitation alter production of cell-to-cell signal molecules and rhamnolipid biosurfactant by Pseudomonas aeruginosa
چکیده انگلیسی
In Pseudomonas aeruginosa, rhamnolipid production is controlled by the quorum-sensing system RhlRI, which itself depends on LasRI. These systems use cell-to-cell signal molecules: N-butyryl-l-homoserine lactone (C4-HSL) and N-(3-oxododecanoyl)-l-homoserine lactone (3OC12-HSL), respectively. Whereas both HSLs were produced in M63 medium, rhamnolipid synthesis was not achieved. Phosphate limitation reduced the HSL concentrations, while allowing rhamnolipid production. Hyperosmotic shock applied during the exponential growth phase stopped the accumulation of 3OC12-HSL, and prevented C4-HSL and rhamnolipid production. These defects result from lower expression of genes involved in C4-HSL and rhamnolipid syntheses. The osmoprotectant glycine betaine partially restored C4-HSL and rhamnolipid production.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: FEMS Microbiology Letters - Volume 253, Issue 1, 1 December 2005, Pages 125-131
نویسندگان
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