کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
9209763 1192446 2005 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Balance entre citocinas pro y antiinflamatorias en estados sépticos
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی مراقبت های ویژه و مراقبتهای ویژه پزشکی
پیش نمایش صفحه اول مقاله
Balance entre citocinas pro y antiinflamatorias en estados sépticos
چکیده انگلیسی
From the start of sepsis symptomatology until the day 28, and when clinical disturbances of SIRS are already gone, the global balance among the pro- inflammatory and anti-inflammatory mo-lecules studied aims at a very important increase of anti-inflammatory molecules. The role of TNF-α and IL-1 ß in sepsis seems to be that of triggering factors, but subsequently both lack of pathogenic role. sTNFR-I, sTNFR-II and IL-1 ar have great prognostic value and their levels are related to the development of MODS and to the failure of every organ system. Higher levels of IL-10 and TFR-ß are also related to mortality, although in late phases. Future therapeutic interventions should take into account the fact that sepsis is a dynamic process.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Medicina Intensiva - Volume 29, Issue 3, April 2005, Pages 151-158
نویسندگان
, , , , , ,