کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
9217804 | 1199536 | 2005 | 9 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Clindamycin in dentistry: More than just effective prophylaxis for endocarditis?
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موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
دندانپزشکی، جراحی دهان و پزشکی
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چکیده انگلیسی
Clindamycin is a broad-spectrum antibiotic with activity against aerobic, anaerobic, and β-lactamase-producing pathogens. This antibiotic has been used for many years as prophylactic treatment during dental procedures to prevent endocarditis. However, the spectrum and susceptibility of the bacteria species involved in dental infections indicate that clindamycin would also be an effective treatment option for these conditions. In addition to its antiinfective properties, clindamycin has high oral absorption, significant tissue penetration, including penetration into bone, and stimulatory effects on the host immune system. This review discusses the microbiologic and clinical evidence supporting the efficacy and safety of clindamycin for the successful management of dental infections.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology - Volume 100, Issue 5, November 2005, Pages 550-558
Journal: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology - Volume 100, Issue 5, November 2005, Pages 550-558
نویسندگان
Itzhak MD, MSc, Mike A.O. PhD, BDS, FDSRCS, FRCPath, George K.B. DDS, PhD, MD, FRCD(C), FRCS(C), FACS, Marjorie DMD, L.P. BDS, DDS, FRCPath, FCDSHK, Jorge DDS,