کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
9221475 | 1200450 | 2005 | 12 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Adjuvant therapies in the treatment of stage II and III malignant melanoma
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
دندانپزشکی، جراحی دهان و پزشکی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Adjuvant therapies in the treatment of stage II and III malignant melanoma Adjuvant therapies in the treatment of stage II and III malignant melanoma](/preview/png/9221475.png)
چکیده انگلیسی
Background: The incidence of cutaneous melanoma has increased during the past three decades. The development of sentinel lymph node biopsy has facilitated better staging. Despite these improvements, 5-year survival rates for American Joint Committee on Cancer stage II and III disease range from 50%-90%. Methods: A review of the current literature concerning adjuvant therapies in patients with stage II and III malignant melanomas was undertaken. Results: The focus of adjuvant therapies has shifted from radiotherapy, BCG and levamisole to newer biological agents. Interferon, interleukin and vaccines have been evaluated but none of these agents have demonstrated an increase in overall survival in patients with stage II and III melanoma. Interferon can prolong disease-free interval. Conclusion: At present, no adjuvant therapy improves overall survival in patients with stage II and III melanoma. New staging allows more accurate stratification of patients for clinical trials
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: The Surgeon - Volume 3, Issue 4, August 2005, Pages 245-256
Journal: The Surgeon - Volume 3, Issue 4, August 2005, Pages 245-256
نویسندگان
D. Kavanagh, A.D.K. Hill, B. Djikstra, R. Kennelly, E.M.W. McDermott, N.J. O'Higgins,