کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
924336 | 921217 | 2010 | 7 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Increased saccadic rate during smooth pursuit eye movements in patients at Ultra High Risk for developing a psychosis Increased saccadic rate during smooth pursuit eye movements in patients at Ultra High Risk for developing a psychosis](/preview/png/924336.png)
Abnormalities in eye tracking are consistently observed in schizophrenia patients and their relatives and have been proposed as an endophenotype of the disease. The aim of this study was to investigate the performance of patients at Ultra High Risk (UHR) for developing psychosis on a task of smooth pursuit eye movement (SPEM). Forty-six UHR patients and twenty-eight age and education matched controls were assessed with a task of SPEM and psychiatric questionnaires. Our results showed that both the corrective and non-corrective saccadic rates during pursuit were higher in the UHR group. There were however no differences in smooth pursuit gain between the two groups. The saccadic rate was related to positive UHR symptoms. Our findings indicate that abnormalities in SPEM are already present in UHR patients, prior to a first psychotic episode. These abnormalities occur only in the saccadic system.
Journal: Brain and Cognition - Volume 73, Issue 3, August 2010, Pages 215–221