کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
925192 | 921315 | 2006 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
A quantitative near-infrared spectroscopy study: A decrease in cerebral hemoglobin oxygenation in Alzheimer’s disease and mild cognitive impairment
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
علم عصب شناسی
علوم اعصاب شناختی
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چکیده انگلیسی
A newly developed quantitative near-infrared spectroscopy (NIRS) system was used to measure changes in cortical hemoglobin oxygenation during the Verbal Fluency Task in 32 healthy controls, 15 subjects with mild cognitive impairment (MCI), and 15 patients with Alzheimer’s disease (AD). The amplitude of changes in the waveform, which was quantitatively calculated by a signal processing method, was significantly lower in the frontal, and the bilateral parietal areas in the AD group, whereas that in the MCI group was significantly lower only in the right parietal area. The NIRS system may be a potential tool for the primary screening of AD.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Brain and Cognition - Volume 61, Issue 2, July 2006, Pages 189–194
Journal: Brain and Cognition - Volume 61, Issue 2, July 2006, Pages 189–194
نویسندگان
Heii Arai, Maki Takano, Koichi Miyakawa, Tsuneyoshi Ota, Tadashi Takahashi, Hirokazu Asaka, Tsuneaki Kawaguchi,