کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
9252765 1210871 2005 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
The role of oxidative stress in NASH and fatty liver model
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی بیماری‌های گوارشی
پیش نمایش صفحه اول مقاله
The role of oxidative stress in NASH and fatty liver model
چکیده انگلیسی
But simultaneous DFO treatment for one week reduced this elevation of ALT as well as MDA accumulation in the liver. Feeding rats a CDAA diet for 14 weeks led to the development of severe liver fibrosis and preneoplastic lesions detected as enzyme-altered lesions. DFO treatment also prevented the expression of activated stellate cells, resulting in the reduction of liver fibrosis as well as reducing the development of preneoplastic lesions. These results indicate that iron chelation can reduce the development of preneoplastic lesions in a CDAA diet model.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Hepatology Research - Volume 33, Issue 2, October 2005, Pages 128-131
نویسندگان
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