کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
9261546 | 1214300 | 2005 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
The possible etiopathogenic genes of Sjögren's syndrome
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
موضوعات مرتبط
علوم زیستی و بیوفناوری
ایمنی شناسی و میکروب شناسی
ایمونولوژی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: The possible etiopathogenic genes of Sjögren's syndrome The possible etiopathogenic genes of Sjögren's syndrome](/preview/png/9261546.png)
چکیده انگلیسی
Sjögren's syndrome is a chronic autoimmune disease characterized by focal lymphocytic infiltration of lacrimal and salivary glands, but the precise mechanism of this syndrome is unclear. To clarify the pathogenesis of Sjögren's syndrome, the related genes must be identified. In the present study, we investigate the increased expression of genes and molecules related to Sjögren's syndrome and present our findings of cDNA microarray analysis in the mouse model. Furthermore, we present the results of immunohistochemical analysis of salivary glands in the mouse model and patients with Sjögren's syndrome. This approach might open a new discussion of the existence of principal pathogenic molecules in Sjögren's syndrome.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Autoimmunity Reviews - Volume 4, Issue 7, September 2005, Pages 479-484
Journal: Autoimmunity Reviews - Volume 4, Issue 7, September 2005, Pages 479-484
نویسندگان
Masami Takei, Hidetaka Shiraiwa, Takashi Azuma, Yoshio Hayashi, Naoyuki Seki, Shigemasa Sawada,