Transfusion-transmitted infections among multi-transfused patients in Brazil

Conclusions: HCV infection was the most prevalent TTI among MTP, and remains a major health problem for these patients.A dose-effect relationship could be detected between HCV and the number of units transfused. The implementation of measures such as donor education programs, standards for donor selection criteria, and of improved serological screening protocols, paralleled the decline in the prevalence of TTI, specially of HCV, observed in MTP, underscoring the importance of such measures for the reduction of the residual risk of TTI.