Folates en période péri-conceptionnelle et prévention du risque de fente orofaciale : rôle des apports alimentaires en France

Our study further suggests that folates are useful for the prevention of orofacial clefts during the periconceptual period. In our study, the estimated average daily intake of folates (270 mg/day) was below French national recommendations for the prevention of neural tube defects (400 mg/day). Since those insufficient folate intakes during the periconceptual period are not presently met by vitamin supplementation, the solution may come from the food fortification program proposed and implemented by the National Agency for Food Safety (AFSSA).