Inhibition of corneal neovascularization by a peroxisome proliferator-activated receptor-γ ligand

Conclusions. Pioglitazone is effective in decreasing the density of angiogenesis in a VEGF-induced neovascular rat cornea model. There is possibility of even greater effect with higher doses of the drug. Pioglitazone is a promising drug for the treatment of ocular neovascularization.