کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
9368200 1272436 2005 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Lupus eritematoso sistémico pediátrico
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی پریناتولوژی (پزشکی مادر و جنین)، طب اطفال و بهداشت کودک
پیش نمایش صفحه اول مقاله
Lupus eritematoso sistémico pediátrico
چکیده انگلیسی
Pediatric systemic lupus erythematosus (pSLE) is a chronic mutisystemic autoimmune disease with complex clinical manifestations. Although the presentation, clinical manifestations, immunological findings and treatment issues of pSLE are similar to those of adult SLE patients, there are special issues which need to be considered when dealing with SLE in children. During the last decade survival has improved remarkably as a result of earlier diagnosis, recognition of milder disease and better approaches to therapy. However, pSLE remains a potentially serious condition. Although the pathogenesis of SLE remains poorly understood, susceptibility involves a combination of environmental, hormonal and genetic factors.Better understanding of SLE pathogenesis will hopefully lead to more specific and less toxic therapies for this disease.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Anales de Pediatría - Volume 63, Issue 4, October 2005, Pages 321-329
نویسندگان
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