کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
937071 1475225 2006 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Capsaicin-sensitive afferent vagal fibers are involved in concurrent taste aversion learning
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب رفتاری
پیش نمایش صفحه اول مقاله
Capsaicin-sensitive afferent vagal fibers are involved in concurrent taste aversion learning
چکیده انگلیسی

Taste aversion learning (TAL) is a type of learning characterized by rejection of a gustatory/flavor stimulus as a consequence of its pairing with visceral discomfort and malaise. TAL can be established in the laboratory by two different behavioral procedures, concurrent or sequential. Neural mechanisms of these learning modalities remain to be elucidated, but several studies have discussed the implication of various anatomical structures, including the vagus nerve. The aim of this study was to examine the role of capsaicin-sensitive vagal afferent fibers in concurrent (Experiment 1) and sequential (Experiment 2) TAL in Wistar rats. Results showed that perivagal administration of capsaicin (1 mg of capsaicin dissolved in 1 ml of vehicle (10% Tween 80 in oil)) blocked acquisition of concurrent but not sequential TAL. These data support the hypothesis of two different modalities of TAL mediated by distinct neurobiological systems, with vagal nerve participation only being essential in concurrent TAL.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Neurobiology of Learning and Memory - Volume 86, Issue 3, November 2006, Pages 349–352
نویسندگان
, , , ,