کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
937873 924552 2012 10 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Stress effects on memory: An update and integration
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب رفتاری
پیش نمایش صفحه اول مقاله
Stress effects on memory: An update and integration
چکیده انگلیسی

It is well known that stressful experiences may affect learning and memory processes. Less clear is the exact nature of these stress effects on memory: both enhancing and impairing effects have been reported. These opposite effects may be explained if the different time courses of stress hormone, in particular catecholamine and glucocorticoid, actions are taken into account. Integrating two popular models, we argue here that rapid catecholamine and non-genomic glucocorticoid actions interact in the basolateral amygdala to shift the organism into a ‘memory formation mode’ that facilitates the consolidation of stressful experiences into long-term memory. The undisturbed consolidation of these experiences is then promoted by genomic glucocorticoid actions that induce a ‘memory storage mode’, which suppresses competing cognitive processes and thus reduces interference by unrelated material. Highlighting some current trends in the field, we further argue that stress affects learning and memory processes beyond the basolateral amygdala and hippocampus and that stress may pre-program subsequent memory performance when it is experienced during critical periods of brain development.


► Stress effects on memory depend on the timing of stress relative to learning.
► Rapid, non-genomic glucocorticoid actions lead to a ‘memory formation mode’.
► Slow, genomic glucocorticoid actions promote a ‘memory storage mode’.
► Stress and stress hormones affect memory beyond the hippocampus.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Neuroscience & Biobehavioral Reviews - Volume 36, Issue 7, August 2012, Pages 1740–1749
نویسندگان
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