An integrative model of tinnitus based on a central gain controlling neural sensitivity

▶ Central changes after sensory deprivation could result from homeostatic plasticity. ▶ Homeostatic plasticity preserves the stability of neural activity and neural coding efficiency. ▶ Homeostatic plasticity could result in aberrant perceptions such as tinnitus. ▶ Tinnitus could result from a trade-off between a central gain increase and neural noise.