کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
9382027 | 1278747 | 2005 | 13 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Treatment-limiting toxicities associated withnucleoside analogue reverse transcriptase inhibitor therapy: A prospective, observational study
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کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
سیاست های بهداشت و سلامت عمومی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Treatment-limiting toxicities associated withnucleoside analogue reverse transcriptase inhibitor therapy: A prospective, observational study Treatment-limiting toxicities associated withnucleoside analogue reverse transcriptase inhibitor therapy: A prospective, observational study](/preview/png/9382027.png)
چکیده انگلیسی
The results of this study in patients with HIV-1 recruited in the10 Recover Study and undergoing HAART suggest that long-term treatment with NRTIs is associated with AEs (lipoatrophy, peripheral neuropathy, and lipodystrophy), with morphologic disorders (lipoatrophy, lipodystrophy) being the most common AEs leading to discontinuation. Minimizing these AEs by switching to an NRTI not associated with these AEs (eg, tenofovir) would contribute to adherence and hence efficacy of long-term HAART.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Current Therapeutic Research - Volume 66, Issue 2, MarchâApril 2005, Pages 117-129
Journal: Current Therapeutic Research - Volume 66, Issue 2, MarchâApril 2005, Pages 117-129
نویسندگان
MD PhD Palacios, MD Santos, MD Camino, MD Arazo, MD Torres Perea, MD Echevarrfa, MD PhD Ribera, MD, PhD Sánchez de la Rosa, MD PhD Moreno Guillen, Recover Study Group Recover Study Group,