کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
9402467 1288541 2005 12 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Transgenic and gene knock-out techniques and burn research
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی عمل جراحی
پیش نمایش صفحه اول مقاله
Transgenic and gene knock-out techniques and burn research
چکیده انگلیسی
The development of transgenic technology has given researchers a powerful tool to examine biological effects, and the response to injury is no exception. Techniques such as pronuclear injection, targeted homologous recombination, and Cre/loxP gene excision are being used to construct animals with specific genetic designs; these are exploited to learn the role of genes in the response to severe burn. We review the construction of transgenic animals, pitfalls and benefits of this relatively new technique, and how this technique has been used in burn research.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Surgical Research - Volume 123, Issue 2, February 2005, Pages 328-339
نویسندگان
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