Keywords: ناک اوت; BMAL1; brain and muscle ARNT-like 1; CCG; clock-controlled genes; CLOCK; circadian locomoter output cycles protein kaput; CRY; Cryptochrome; KO; knock-out; NAD+; nicotinamide adenine dinucleotide (oxidized); NADH; nicotinamide adenine dinucleotide (reduce
مقالات ISI ناک اوت (ترجمه نشده)
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Keywords: ناک اوت; CCL; chemokine (CC-motif) ligand; CD; cluster of differentiation; CXCL; chemokine (CXC-motif) ligand; IL; interleukin; KD; knock-down; KO; knock-out; LPS; lipopolysaccharide; NT; non-target; PC; proprotein convertase; STAT; signal transducer and activator
Keywords: ناک اوت; CF; climbing fiber; dLGN; dorsal lateral geniculate nucleus; EPSC; excitatory postsynaptic current; IONC; infraorbital nerve cut; KO; knock-out; mGluR1; metabotropic glutamate receptor subtype 1; PC; Purkinje cell; PF; parallel fiber; PrV; principal senso
Keywords: ناک اوت; Opioids; Analgesia; Adverse effects; Mechanisms; Constipation; Nausea; Vomiting; Respiratory depression; 5-HT; 5-hydroxytryptamine; 7TMRs; 7-transmembrane spanning G-protein coupled receptors; AC; adenylyl cyclase; β-arr1; β-arrestin1; β-arr2; β-arres
Keywords: ناک اوت; 3-MC; 3-methylcholanthrene; Ah; aryl hydrocarbon; AhE; aryl hydrocarbon receptor; AP-1; activator protein-1; ARE; antioxidant response element; ATF4; activating transcription factor 4; β-NF; β-naphthoflavone; β-NF-RE; β-NF-responsive element; β-TRCP;
Keywords: ناک اوت; Loperamide; Opioid receptor; Pain; Nav1.7; Sodium channel; MOR; mu-opioid receptor; VGSCs; Voltage-gated sodium channels; HEK; human embryo kidney; KO; knock-out; PWF; paw withdrawal frequency; CFA; complete Freund's adjuvant; DRG; dorsal root ganglion; P
Hierarchical identification of bioactive components in a medicinal herb by preparative high-performance liquid chromatography and selective knock-out strategy
Keywords: ناک اوت; Safflower; Herb; Contribution; Component; High-performance liquid chromatography; Knock-out;
Keywords: ناک اوت; ACC; acetyl-CoA carboxylase; Alcat1; ER-associated monolyso-CL acyltransferase; ATP; Adenosin triphosphate; AU; Arbitrary Unit; β-HAD; beta-hydroxyacyl CoA dehydrogenase; CHL; cholesterol; CL; cardiolipin; CLS; cardiolipin synthase; COX; Cytochrome c oxi
Keywords: ناک اوت; ACVR; activin A receptor; ALK; activin receptor-like kinase; BMP; bone morphogenetic protein; BOP; blast over pressure; COX; cyclo-oxygenase; CT; computed tomography; ECM; extracellular matrix; FOP; fibrodysplasia ossificans progressiva; HES; hydroxy-ethy
Keywords: ناک اوت; SIBLING; Small Integrin-Binding Ligand N-linked Glycoprotein; BSP; bone sialoprotein; OPN; osteopontin; TNAP; tissue-nonspecific alkaline phosphatase; PPi; inorganic pyrophosphate; ANK; progressive ankylosis protein; ENPP1; ectonucleotide pyrophosphatase
Keywords: ناک اوت; FBE; Actin free barbed ends; ASC; Apoptosis-associated Speck protein with CARD domain; CT; citrate transporter; ME; cytosolic NADP-dependent malic enzyme; DCF-DA; 2;7-dihydrodichloro-fluorescein diacetate; FAK; focal adhesion kinase; ER; endoplasmic retic
Keywords: ناک اوت; APCs; antigen presenting cells; ATP; adenosine triphosphate; BBB; blood brain barrier; BM; bone marrow; CB; cord blood; CNS; central nervous system; CSF; cerebrospinal fluid; DAMPs; danger associated molecular pattern molecules; DCs; dendritic cells; EAE;
Keywords: ناک اوت; Abcg1; ATP-binding cassette transporter G1; BCA; bicinchoninic acid; C; carbon atoms; Cyp51; lanosterol 14α-demethylase or 14α-sterol demethylase; CypB; cyclophilin B; db; double bonds; Dhcr24; desmosterol reductase or sterol â24-reductase; Elovl 2; e
Keywords: ناک اوت; (2-AG); 2-arachidonoyl-glycerol; (â9-THC); delta-9-tetrahydrocannabinol; (AA); Alko Alcohol preferring; (ABHD); alpha/beta hydrolase domain-containing protein; (ADE); alcohol deprivation effect; (AEA); N-arachidonoylethanolamine; (CB1); cannabinoid rece
Keywords: ناک اوت; BED; binge eating disorder; BSA; bovine serum albumin; DA; dopamine; GHSR; growth-hormone secretagogue receptor; HFD; high-fat diet; INT; intermittent; KO; knock-out; LHA; lateral hypothalamic area; NAcc; nucleus accumbens; SEM; standard error of the mean
Keywords: ناک اوت; genes; knee; knock-out; mice; osteoarthritis; therapy
Keywords: ناک اوت; Multivariate pattern analysis; Interpretability; Relevant features; Random forests; Knock-out;
Keywords: ناک اوت; AA; arachidonic acid; ALP; alkaline phosphatase; ALX; G protein-coupled lipoxin A(4) receptor; AMP; adenosine monophosphate; BAT; brown adipose tissue; BMC; bone mineral content; BMD; bone mineral density; BMI; body mass index; CKD; chronic kidney disease
Keywords: ناک اوت; ACE; angiotensin-converting enzyme; ANF; atrial natriuretic factor; BNP; brain natriuretic peptide; DCM-CD; dilated cardiomyopathy with conduction defects; EDMD; Emery-Dreifuss muscular dystrophy; EHT; engineered heart tissue; KI; knock-in; KO; knock-ou
Keywords: ناک اوت; Abs; antibodies; Akt; cytoplasmic serine-threonine kinase from Ak mouse strain thymoma; Cbl; cobalamin; Cbl-D; Cbl-deficient; CNS; central nervous system; CSF; cerebrospinal fluid; DMSO; dimethyl sulfoxide; Dpl; Doppel; EGF; epidermal growth factor; GFAP;
Keywords: ناک اوت; ACh; acetylcholine; AP; action potentials; DA; dopamine; ISI; interspike interval; KO; knock-out; LDTg; laterodorsal tegmental nucleus; LFHB; low-firing, high-bursting; LFLB; low-firing, low-bursting; NAcc; nucleus accumbens; nAChRs; nicotinic acetylcholi
Keywords: ناک اوت; ACAT; acyl-CoA cholesterol acyltransferase; ACC; acetyl CoA carboxylases; ACLY; ATP citrate lyases; ACSL; acyl CoA synthetases long chain family; ADRP; adipose differentiation related protein; AGP; advanced glycation end products; AGPAT; acylglycerophosph
Keywords: ناک اوت; ANOVA; analysis of variance; KO; knock-out; PRL; prolactin; PRL-R; PRL-receptor; PRL KO; PRL null-mutant; PRL-R KO; PRL-R null-mutant; WT; wild-type; prolactin; prolactin receptor; post operative model; pain; sex-dependence;
Keywords: ناک اوت; Transgenic; Knock-out; Conditional somatic mutagenesis; Cre; Androgen; Stem cells;
The cyclic AMP phosphodiesterase RegA critically regulates encystation in social and pathogenic amoebas
Keywords: ناک اوت; PDE; phosphodiesterase; cAMP; 3â²5â²-adenosine monophosphate; PKA; cAMP dependent protein kinase; ACG; adenylate cyclase G; AcrA; adenylate cyclase R; MRSA; methicillin resistant Streptococcus aureus; Acas; Acanthamoeba castellani; Ddis; Dictyostelium d
Biological function of a gC1qR homolog (EcgC1qR) of Exopalaemon carinicauda in defending bacteria challenge
Keywords: ناک اوت; Exopalaemon carinicauda; Globular heads of C1q; CRISPR/Cas9; Knock-out;
CRISPR/Cas9-mediated deletion of EcMIH shortens metamorphosis time from mysis larva to postlarva of Exopalaemon carinicauda
Keywords: ناک اوت; Exopalaemon carinicauda; CRISPR/Cas9; Molt-inhibiting hormone; Knock-out;
Deletion of serine racemase confers D-serine -dependent resilience to chronic social defeat stress
Keywords: ناک اوت; Depression; D-Serine; Serine racemase; Stress resilience; BDNF; brain-derived neurotrophic factor; BSA; bovine serum albumin; CSDS; chronic social defeat stress; CSF; cerebrospinal fluid; DG; dentate gyrus; ECL; enhanced chemiluminescence; FST; forced swi
Physiological roles of CNS muscarinic receptors gained from knockout mice
Keywords: ناک اوت; Cholinergic; Muscarinic; Mice; Knockout; Knock-out; Null mutation; CIN; cholinergic interneuron; CAMKIIα; Ca2+/calmodulin-dependent protein kinase IIα; EPSP; excitatory postsynaptic potentials; HPA; hypothalamic-pituitary-adrenocortical; MAPK; mitogen-a
Deletion of Orai2 augments endogenous CRAC currents and degranulation in mast cells leading to enhanced anaphylaxis
Keywords: ناک اوت; ORAI2; Knock-out; Calcium; Mast cell activation; Antigen; Compound 48/80; MRGPRB2; Chloroquine; CRAC current; Store-operated Ca2+ entry; Beta-hexosaminidase; Systemic anaphylaxis;
New in vitro model derived from brain-specific Mut-/- mice confirms cerebral ammonium accumulation in methylmalonic aciduria
Keywords: ناک اوت; 2-MCA; 2-methylcitrate; AKG; α-ketoglutarate; BBB; blood-brain barrier; CSF; cerebrospinal fluid; CNS; central nervous system; cTIN; chronic tubulointerstitial nephritis; DIV; day in vitro; FGF; fibroblast growth factor; GalC; galactocerebroside; GDH; gl
Regnase-1, an Immunomodulator, Limits the IL-36/IL-36R Autostimulatory Loop in Keratinocytes to Suppress Skin Inflammation
Keywords: ناک اوت; CH; contact hypersensitivity; IL-36R; IL-36 receptor; KC; keratinocyte; KD; knock-down; KO; knock-out; IMQ; imiquimod; Reg1; regnase-1;
NOD1 and NOD2: Molecular targets in prevention and treatment of infectious diseases
Keywords: ناک اوت; AMP; antimicrobial peptide; CARD; caspase activation and recruitment domain; CMV; cytomegalovirus; DC; dendritic cell; ER; endoplasmic reticulum; GlcNAc; N-acetyl-d-glycosamine; GMDP; glucosaminyl muramyl dipeptide (N-acetyl-d-glucosaminyl-N-acetyl-d-mura
Transhepatic bile acid kinetics in pigs and humans
Keywords: ناک اوت; Bile acids; TGR5; Porcine; Postprandial; Portal concentrations; BAs; bile acids; ASBT; apical sodium-dependent bile acid transporter; OST; organic solute transporter; NTCP; taurocholate cotransporting polypeptide; OATP; organic anion transporting polypept
Experimental design and data-analysis in label-free quantitative LC/MS proteomics: A tutorial with MSqRob
Keywords: ناک اوت; CPTAC; Clinical Proteomic Technology Assessment for Cancer Network; DDA; data-dependent acquisition; DIA; data-independent acquisition; FC; fold change; FDR; false discovery rate; HCD; higher-energy collisional dissociation; IQR; interquartile range; KO;
Autophagy as a pharmacological target in hematopoiesis and hematological disorders
Keywords: ناک اوت; 3-MA; 3-methyladenine; ALL; acute lymphoblastic leukemia; AMKL; acute megakaryoblastic leukemia; AML; acute myeloid leukemia; AMPK; 5â²-adenosine monophosphate-activated protein kinase; APL; acute promyelocytic leukemia; Atg; autophagy-related proteins;
Genotype-functional-phenotype correlations in photoreceptor guanylate cyclase (GC-E) encoded by GUCY2D
Keywords: ناک اوت; Cyclic GMP; Genotype-phenotype correlation; Guanylate cyclase; GUCY2D; Mutation; Photoreceptor; Retinal diseases; AAV; adeno-associated virus; ad; autosomal dominant; ar; autosomal recessive; BSP; bone spicule-like pigmentation; CCD; cyclase catalytic dom
Regular ArticlesEstablishment of CRISPR/Cas9 in Alternaria alternata
Keywords: ناک اوت; Alternaria; Knock-out; CRISPR; Uracil;
RecET recombination system driving chromosomal target gene replacement in Zymomonas mobilis
Keywords: ناک اوت; Dehydrogenase gene; Electroporation; Ethanol; Genetic manipulation; Gram negative; Industrial applications; Knock-out; Primer; Production; Recombination; Vector;
Chronic mild stress impairs latent inhibition and induces region-specific neural activation in CHL1-deficient mice, a mouse model of schizophrenia
Keywords: ناک اوت; Acb-core; nucleus accumbens core; Acb-shell; nucleus accumbens shell; ANOVA; analysis of variance; BLA; basolateral amygdala; CER; conditioned emotional response; CHL1; Close Homolog of L1; CMS; chronic mild stress; CR; conditioned response; CS; condition
Original articleLong-term treatment with chaethomellic acid A reduces glomerulosclerosis and arteriolosclerosis in a rat model of chronic kidney disease
Keywords: ناک اوت; CAA; chaethomellic acid A; CKD; chronic kidney disease; ECM; extracellular matrix proteins; EMT; epithelial-to-mesenchymal transition; ESRD; end-stage renal disease; IRI; renal ischemia-reperfusion injury; KO; knock-out; RMR; 5/6 renal mass reduction; SBP
Increased temporal discounting after chronic stress in CHL1-deficient mice is reversed by 5-HT2C agonist Ro 60-0175
Keywords: ناک اوت; 5-HT; 5-hydroxytryptamine (serotonin); Acb-core; nucleus accumbens core; Acb-shell; nucleus accumbens shell; ANOVA; analysis of variance; AUC; area under the normalized TD curve; CHL1; close homolog to L1; CUS; chronic unpredictable stress; DA; dopamine,
Forebrain knock-out of torsinA reduces striatal free-water and impairs whole-brain functional connectivity in a symptomatic mouse model of DYT1 dystonia
Keywords: ناک اوت; cKO; conditional knock-out; dMRI; diffusion magnetic resonance imaging; FC; functional connectivity; FW; free-water; KI; knock-in; KO; knock-out; MDT; free-water corrected mean diffusivity; rsfMRI; resting-state functional magnetic resonance imaging; SCI;
ArtÃculo originalLa inhibición de la PI3Kγ protege contra la miocardiopatÃa diabética en ratonesPI3Kγ Inhibition Protects Against Diabetic Cardiomyopathy in Mice
Keywords: ناک اوت; Diabetes mellitus; MiocardiopatÃa; Fármacos en investigación; ProteÃna PI3Kγ; Ratón; Diabetes mellitus; Cardiomyopathy; Investigational drugs; PI3Kγ protein; Mouse; DM; diabetes mellitus; KD; sin actividad de cinasa (kinase-dead); KO; knock-out; MC
MTUS1, a gene encoding angiotensin-II type 2 (AT2) receptor-interacting proteins, in health and disease, with special emphasis on its role in carcinogenesis
Keywords: ناک اوت; Ang II; angiotensin II; ATIP; angiotensin II (AT2) receptor-interacting protein; AT2; angiotensin II receptor type 2; BTCC; bladder transitional cell carcinoma; CNV; copy number variant; ERK; extracellular-regulated kinase; ESCC; esophageal squamous cell
ReviewTransient receptor potential (TRP) channel function in the reproductive axis
Keywords: ناک اوت; Reproduction; Hypothalamus; Pituitary; Gonads; TRP channels; TRPC channels; TRPC5; Knock-out; Plasticity; Gonadotropes; Kisspeptin neurons; GnRH neurons; Genetic labeling; Ca2+ imaging; Genetic Ca2+ indicator; GCaMP3; Whole-cell patch clamp; RNA-sequencin
Cognitive impairments associated with alterations in synaptic proteins induced by the genetic loss of adenosine A2A receptors in mice
Keywords: ناک اوت; Adenosine A2A; Cognition; Aging; Neurogenesis; Synaptic function; ADHD; Attention deficit/hyperactivity disorder; BrdU; Bromodeoxyuridine; CNS; Central nervous system; CS; Conditioned stimulus; CA1; Cornu ammonis 1; CA3; Cornu ammonis 3; DG; Dentate gyrus
IL-17 contributes to the pathogenesis of obliterative bronchiolitis via regulation of M1 macrophages polarization in murine heterotopic trachea transplantation models
Keywords: ناک اوت; OB; obliterative bronchiolitis; H&E; hematoxylin-eosin; HTT; heterotopic trachea transplantation; KO; knock-out; LPS; lipopolysaccharide; WT; wild-type; BMDMs; bone marrow-derived macrophages; IL-17; Macrophages; Obliterative bronchiolitis; Trachea transp
Research PaperCapsaicin protects cortical neurons against ischemia/reperfusion injury via down-regulating NMDA receptors
Keywords: ناک اوت; BBB; blood-brain barrier; DIV; days in vitro; DMSO; dimethyl sulphoxide; DRG; dorsal root ganglion; KO; knock-out; LDH; lactate dehydrogenase; MCAO; middle cerebral artery occlusion; MPPÂ +; Â 1-methyl-4-phenylpyridinium; NMDA; N-methyl-d-aspartic acid; P
TRPV4 ION Channel Is Associated with Scleroderma
Keywords: ناک اوت; KO; knock-out; PBS; phosphate buffered saline; α-SMA; α-smooth muscle actin; SSc; scleroderma; TRP; transient receptor potential; TRPV4; transient receptor potential cation channel subfamily V member 4; WT; wild type;