کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
9424163 | 1295252 | 2005 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Procedure for minimizing stress for fMRI studies in conscious rats
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
علم عصب شناسی
علوم اعصاب (عمومی)
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Procedure for minimizing stress for fMRI studies in conscious rats Procedure for minimizing stress for fMRI studies in conscious rats](/preview/png/9424163.png)
چکیده انگلیسی
Functional magnetic resonance imaging (fMRI) in conscious animals is evolving as a critical tool for neuroscientists. The present study explored the effectiveness of an acclimation procedure in minimizing the stress experienced by the animal as assessed by alterations in physiological parameters including heart rate, respiratory rate, and serum corticosterone levels. Results confirm that as the stress of the protocol is minimized, there is a significant decrease in head movements and enhancement in data quality. The feasibility of improving the quality of fMRI data acquired in alert rats by utilizing a relatively simple technique is presented.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Neuroscience Methods - Volume 148, Issue 2, 30 October 2005, Pages 154-160
Journal: Journal of Neuroscience Methods - Volume 148, Issue 2, 30 October 2005, Pages 154-160
نویسندگان
Jean A. King, Timothy S. Garelick, Mathew E. Brevard, Wei Chen, Tara L. Messenger, Timothy Q. Duong, Craig F. Ferris,